Sie befinden sich hier

Inhalt

Wednesday, 4 September 2019

16:00 - 17:00

Registration

Keynote Lectures and Festive Opening

Chair: Ursula Ravens (Institute for Experimental Cardiovascular Medicine (IEKM), Freiburg)

17:00 - 17:15

Peter Kohl (Director of Research of the University Heart Centre Freiburg-Bad Krozingen, Director of the IEKM) Welcome addresses

17:15 - 18:00

Donald M. Bers (UC Davis Health) Cardiac electro-mechanical cross-talk: what's new?

18:00 - 18:45

Thomas Eschenhagen (UKE Hamburg) Cardiac mechanics matters: models and muddles

18:45 - 19:00

Wrap-up

19:00 - 21:00

Reception Prometheus Hall

Thursday, 5 September 2019

09:00 - ...

Registration

09:15 - 09:30

Remi Peyronnet (IEKM, Freiburg) MEC2019

Session 1: Mechano-Sensitive Ion Channels

Chair: Boris Martinac (Sydney)

09:30 - 10:00

Wei-Zheng Zeng (Scripps Research, La Jolla) Piezo and arterial baro-reception

10:00 - 10:30

Jack Rubinstein (Cincinatti) TRP channels as regulators of cardiac hypertrophy

10:30 - 11:00

Marc Freichel (Heidelberg) Regulating pathological cardiac remodeling via TRPC channels and new players in endo-lysosomal Ca2+ signaling

 

Coffee and Posters

11:30 - 12:00

Niels Decher (Marburg) Arrhythmogenic mutation in human TREK-1: conversion of a SAK to a hypersensitive SAC

12:00 - 12:30

Gentaro Iribe (Okayama) Role of nucleotide signalling in mechano-sensitive responses of organelle and cellular mechanisms

 

Lunch and Posters

Session 2: Stretch Effects on other Molecular Mechanisms

Chair: Gudrun Antoons (Maastricht)

14:00 - 14:30

Thomas Iskratsch (London) Cardiomyocyte - ECM interactions: roles of muscle and non-muscle myosin contractions

14:30 - 15:00

Farah Sheikh (UCSD) Mechanical modulation of cell junctions: relevance for cardiac electrophysiology

15:00 - 15:30

Michele Miragoli (Parma) Mitochondrial Mechanosensor Microdomains in Cardiovascular Disorders

 

Tea and Posters

16:00 - 16:30

Michael Gotthardt (MDC, Berlin) A Visual and Biomechanical Approach to Sarcomere Dynamics

16:30 - 17:00

Kenneth Campbell (Kentucky) Length-dependent activation in human material

17:00 - 17:30

Two presentations selected from abstracts (2 x 10+5 min)

Poster Session

17:30 - 19:30

Posters with refreshments, and nibbles, and more…

Friday, 6 September 2019

Session 3: Methods and Concepts for Quantifying Cardiac Mechanics

Chair: Delphine Dean (Clemson)

09:00 - 09:30

Ramona Emig (IEKM, Freiburg) Light-tuneable hydrogels

09:30 - 10:00

Ye Chen-Izu (UC Davis) Mechanical load effects on AP, [Ca2+]i, and contraction revealed using patch-clamp-in-gel

10:00 - 10:30

Periklis Pantazis (London) Piezo1-based fluorescent reporter for visualizing mechanical stimuli

 

Coffee and Posters

11:00 - 11:30

TBC Stretch-induced compliance: a novel adaptive biological mechanism following acute cardiac load

11:30 - 12:00

Leonardo Sacconi (Florence) Random Access Confocal Microscopy for cardiac research

 

Lunch and Posters

Session 4: Cell and Tissue Level MEC

Chair: Alex Quinn (Halifax)

13:30 - 14:00

Anastasia Khokhlova (Yekaterinburg) Transmural differences in cardiac electro-mechanics

14:00 - 14:30

Takuro Tomita (Matsumoto) TRPC3-Nox2 functional coupling regulates cardiac elasticity

14:30 - 15:00

Diane Fatkin (Sydney) Atrial endocardial TRPC channels and load-dependent endocardial/myocardial cross-talk

 

Tea and Posters

15:30 - 16:00

Kate Herum (UCSD) Mechanical regulation of cardiac fibroblast phenotypes

16:30 - 17:00

Ming Guo (MIT) Cell contraction induces long-ranged stress changes in the extracellular matrix

17:00 - 17:30

Two presentations selected from abstracts (2 x 10+5 min)

18:00 - ...

Optional: Guided walking tour of historic Freiburg or Tour of IEKM

Saturday, 7 September 2019

Session 5: MEC & Arrhythmias: Organ Level

Chair: Andrew McCulloch (UCSD)

09:00 - 09:30

Eilidh MacDonald (Halifax) MEC in Zebrafish: Utility and Limitations for pacemaker studies

09:30 - 10:00

Callum Johnston (IEKM, Freiburg) Opto-Acoustic Imaging of 3D Cardiac Electrophysiology

10:00 - 10:30

Denis Loiselle (Auckland) Frank-Starling reloaded

 

Coffee and Posters

11:00 - 11:30

Jeffrey Holmes (Virginia) Mechanics, dynamics and therapeutic modification of myocardial infarct scar

11:30 - 12:00

William Louch (Oslo) Wall stress induced disturbance in cardiomyocyte ultrastructure

 

Lunch and Posters

Session 6: MEC & Arrhythmias: Translational Aspects

Chair: Crystal Ripplinger (UC Davis)

13:00 - 13:30

Paul Volders (Maastricht) Neuro-mechanical cross-talk in proarrhythmicity of drug-induced LQT syndrome

13:30 - 14:00

Pier Lambiase (London) Structural remodeling and conduction velocity dynamics in human left atrium: relation with reentrant mechanisms sustaining AF

14:00 - 14:30

Esther Pueyo (Zaragoza) The interplay of autonomic and mechanical modulation of ventricular repolarization in human

 

Tea and Posters

Closing Session

Chair: Peter Kohl (IEKM, Freiburg)

15:00 - 15:15

Donald M. Bers (UC Davis Health) What we've learned and what should we focus on next in terms of mechanisms

15:15 - 15:30

Thomas Eschenhagen (UKE Hamburg) What we've learned and what should we focus on next in terms of clinical relevance

15:30 - 16:00

Discussion, Participant feedback

17:30 - 00:00

Meeting Dinner and Dance at Peterhofkeller

17:30 - 18:00

Reception

18:00 - 18:15

Poster Awards

18:15

Dinner

 


Kontextspalte