Wednesday, 21 September 2016 | |||||
Festive Opening of the Institute for Experimental Cardiovascular Medicine in FreiburgChair: Ursula Ravens (Freiburg) | |||||
17:00 – 17:45 | Welcome addresses by:
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17:45 – 18:15 | Kit Parker (Wyss Institute at Harvard University, Boston): Cardiovascular Engineering: Macro to Nano | ||||
18:15 – 18:45 | Natalia Trayanova (Johns Hopkins University, Baltimore): Computational Cardiology: Nano to Macro | ||||
18:45 – 19:00 | Peter Kohl (Director of Research of the University Heart Centre Freiburg-Bad Krozingen, Director of the Institute for Experimental Cardiovascular Medicine) | ||||
19:00 – 21:00 | Reception | ||||
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Thursday, 22 September 2016 | |||||
09:00 – 09:15 | Peter Kohl (Freiburg): Greeting | ||||
09:15 – 09:30 | Ursula Ravens (Freiburg): A tribute to Professor Max Lab | ||||
Session 1: Stretch & StructureChair: Gentaro Iribe (Okayama) | |||||
09:30 – 10:00 | Takashi Mikawa (San Francisco): Mechanical effects on developmental patterning of atrial conduction | ||||
10:00 – 10:30 | Andrew McCulloch (San Diego): Stretch-induced changes in sarcolemmal organisation | ||||
| Coffee and Posters | ||||
11:00 – 11:30 | Eva Rog-Zielinska (London): Structural changes in cell membrane compartments during contraction and relaxation | ||||
11:30 – 12:00 | Stephan Rohr (Bern): Aggravation of cardiac myofibroblast arrhythmogeneicity by mechanical stress | ||||
| Lunch and Posters | ||||
Session 2: Mechano-Sensing Mechanisms in Striated MuscleChair: Fred Sachs (Buffalo) | |||||
13:30 – 14:00 | Malcolm Irving (KCL): Sarcomeric mechanosensing by myosin filaments: Frank-Starling reloaded? | ||||
14:00 – 14:30 | Christopher Ward (Baltimore): Microtubules modulate mechanotransduction in heart muscle | ||||
14:30 – 15:00 | Gudrun Antoons (Maastricht): Stretch-induced modulation of Ca2+ handling in atrial and ventricular myocytes | ||||
| Tea and Posters | ||||
15:30 – 16:00 | Pieter de Tombe (Chicago): Measuring organelle-entrapped calcium in ventricular sarcoplasmic reticulum: new methods and insights | ||||
16:00 – 16:30 | Delphine Dean (Clemson): AFM-based mechanical characterisation of cardiac muscle cells | ||||
Poster Session | |||||
16:30 – 19:00 | With Refreshments, and Nibbles, and more… | ||||
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Friday, 23 September 2016 | |||||
Session 3: Quantifying & Classifying Mechanical StimuliChair: Veronique Meijborg (Amsterdam) | |||||
09:00 – 09:30 | Boris Martinac (Sydney): Single molecule FRET to study pore size and opening mechanism of mechano-sensitive ion channels | ||||
09:30 – 10:00 | Brenton Hoffman (Durham): Construction, imaging, and analysis of FRET-based tension sensors in living cells | ||||
10:00 – 10:30 | Tomaso Zambelli (ETH Zurich): Force-controlled patch clamp of beating cardiac cells | ||||
| Coffee and Posters | ||||
11:00 – 11:30 | Dirk Trauner (Munich): Controlling Biological Pathways with Synthetic Photoswitches | ||||
11:30 – 12:00 | Stefan Luther (Göttingen): Simultaneous Mapping of Electrical and Mechanical Activity in the Non-Uncoupled Langendorff Heart | ||||
| Lunch and Posters | ||||
Session 4: Stretch & Ion HandlingChair: Olga Solovyova (Ekaterinburg) | |||||
13:30 – 14:00 | Mario Delmar (New York): Nanoscale visualization of functional adhesion/excitability nodes at the intercalated disc | ||||
14:00 – 14:30 | Stephane Sebille (Poitiers): Cardiac TRPV2 channels: role in mediating cardiac pathology | ||||
14:30 – 15:00 | Thomas Suchyna (Buffalo): GsMTx-4: Mechanism of MSC inhibition and cardioprotective potential | ||||
| Tea and Posters | ||||
15:30 – 16:00 | Remi Peyronnet (Freiburg): Stretch-activated channels in human heart valves | ||||
16:00 – 16:30 | Yoram Etzion (Ben-Gurion University): Leadless Pacing by Magnetic Actuation of Injected Iron-Microparticles | ||||
| Free Evening or | ||||
17:00 | Guided walking tour of historic Freiburg (optional) | ||||
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Saturday, 24 September 2016 | |||||
Session 5: MEC & Arrhythmias: Animal ModelsChair: Larissa Fabritz (University of Birmingham) | |||||
09:00 – 09:30 | Alex Quinn (Halifax): Mechanically-Induced Ventricular Ectopy and Fibrillation in the Isolated Heart | ||||
09:30 – 10:00 | Ruben Coronel (Amsterdam): Synchronization of repolarization by mechano-electrical coupling in the heart | ||||
10:00 – 10:30 | David Filgueiras-Rama (Madrid): Increased intraventricular pressure favouring sustained re-entry in the swine heart | ||||
| Coffee and Posters | ||||
11:00 – 11:30 | José A. Barrabés (Barcelona): Stretch-activated channel block: effects on cardiac electrophysiology ex- and in-situ | ||||
11:30 – 12:00 | Fanny Vaillant (Bordeaux): The isolated working porcine heart model for the study of mechanical, electrophysiological and metabolic functions. | ||||
| Lunch and Posters | ||||
Session 6: MEC & Arrhythmias in HumanChair: Michael R. Franz (Washington) | |||||
13:30 – 14:00 | Dennis Lau (Adelaide): Acute atrial stretch and pulmonary vein arrhythmogenesis | ||||
14:00 – 14:30 | Cathrin Theis (Mainz): Percutaneous Mitral Valve Repair and Ventricular Arrhythmias | ||||
14:30 – 15:00 | Teri Whitman (Minneapolis): Influence of intracardiac pressure on spontaneous ventricular arrhythmias: lessons from the REDUCEhf trial | ||||
| Tea and Posters | ||||
Closing SessionChair: Peter Kohl (Freiburg) | |||||
15:15 – 15:30 | Mark Marshall (Medtronic): What we’ve learned | ||||
15:30 – 15:45 | Natalia Trayanova (Baltimore): Where we go from here | ||||
15:45 – 16:00 | Discussion, Participant feedback | ||||
| Meeting Dinner and Dance at Peterhofkeller | ||||
17:30 | Reception | ||||
18:00 | Dinner | ||||
19:30 – 00:00 | Entertainment | ||||
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